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Contribution of the Potassium-Chloride Cotransporter KCC2 to the Strength of Inhibition in the Neonatal Rodent Spinal Cord In Vitro
In healthy mature motoneurons (MNs), KCC2 cotransporters maintain the intracellular chloride concentration at low levels, a prerequisite for postsynaptic inhibition mediated by GABA and glycine. KCC2 expression in lumbar MNs is reduced after spinal cord injury (SCI) resulting in a depolarizing shift...
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| Publicado no: | J Neurosci |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6705413/ https://ncbi.nlm.nih.gov/pubmed/25834055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1674-14.2015 |
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