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Contribution of the Potassium-Chloride Cotransporter KCC2 to the Strength of Inhibition in the Neonatal Rodent Spinal Cord In Vitro

In healthy mature motoneurons (MNs), KCC2 cotransporters maintain the intracellular chloride concentration at low levels, a prerequisite for postsynaptic inhibition mediated by GABA and glycine. KCC2 expression in lumbar MNs is reduced after spinal cord injury (SCI) resulting in a depolarizing shift...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Gackière, Florian, Vinay, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705413/
https://ncbi.nlm.nih.gov/pubmed/25834055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1674-14.2015
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