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Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs
Cation-chloride-cotransporters (CCCs) catalyze transport of Cl(-) with K(+) and/or Na(+)across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function. CCCs are targets of clinically important drug...
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| 發表在: | eLife |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7200160/ https://ncbi.nlm.nih.gov/pubmed/32286222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52505 |
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