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Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs

Cation-chloride-cotransporters (CCCs) catalyze transport of Cl(-) with K(+) and/or Na(+)across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function. CCCs are targets of clinically important drug...

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書目詳細資料
發表在:eLife
Main Authors: Reid, Michelle S, Kern, David M, Brohawn, Stephen Graf
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200160/
https://ncbi.nlm.nih.gov/pubmed/32286222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52505
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