Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes three putative ion channels: E, 8a, and 3a(1,2). 3a is expressed in SARS patient tissue and anti-3a antibodies are observed in patient plasma(3–6). 3a has...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Kern, David M., Sorum, Ben, Mali, Sonali S., Hoel, Christopher M., Sridharan, Savitha, Remis, Jonathan P., Toso, Daniel B., Kotecha, Abhay, Bautista, Diana M., Brohawn, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310636/
https://ncbi.nlm.nih.gov/pubmed/32587976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.17.156554
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