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Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model

In Alzheimer's disease (AD), the pathological accumulation of tau appears to be a downstream effect of amyloid β protein (Aβ). However, the relationship between these two proteins and memory loss is unclear. In this study, we evaluated the specific removal of pathological tau oligomers in aged...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Neurosci
Main Authors: Castillo-Carranza, Diana L., Guerrero-Muñoz, Marcos J., Sengupta, Urmi, Hernandez, Caterina, Barrett, Alan D.T., Dineley, Kelly, Kayed, Rakez
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705372/
https://ncbi.nlm.nih.gov/pubmed/25810517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4989-14.2015
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