Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model

In Alzheimer's disease (AD), the pathological accumulation of tau appears to be a downstream effect of amyloid β protein (Aβ). However, the relationship between these two proteins and memory loss is unclear. In this study, we evaluated the specific removal of pathological tau oligomers in aged...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Castillo-Carranza, Diana L., Guerrero-Muñoz, Marcos J., Sengupta, Urmi, Hernandez, Caterina, Barrett, Alan D.T., Dineley, Kelly, Kayed, Rakez
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705372/
https://ncbi.nlm.nih.gov/pubmed/25810517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4989-14.2015
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