Mammalian Target of Rapamycin Signaling Is a Key Regulator of the Transit-Amplifying Progenitor Pool in the Adult and Aging Forebrain

Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles of key intracellular signaling pathways remain vaguely defined. Here, we show that mammalian target of rapamycin (mTOR) signaling is pivotal i...

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Publicado no:J Neurosci
Main Authors: Paliouras, Grigorios N., Hamilton, Laura K., Aumont, Anne, Joppé, Sandra E., Barnabé-Heider, Fanie, Fernandes, Karl J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704835/
https://ncbi.nlm.nih.gov/pubmed/23100423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2248-12.2012
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