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Mammalian Target of Rapamycin Signaling Is a Key Regulator of the Transit-Amplifying Progenitor Pool in the Adult and Aging Forebrain

Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles of key intracellular signaling pathways remain vaguely defined. Here, we show that mammalian target of rapamycin (mTOR) signaling is pivotal i...

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書目詳細資料
發表在:J Neurosci
Main Authors: Paliouras, Grigorios N., Hamilton, Laura K., Aumont, Anne, Joppé, Sandra E., Barnabé-Heider, Fanie, Fernandes, Karl J. L.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704835/
https://ncbi.nlm.nih.gov/pubmed/23100423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2248-12.2012
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