Mammalian Target of Rapamycin Signaling Is a Key Regulator of the Transit-Amplifying Progenitor Pool in the Adult and Aging Forebrain

Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles of key intracellular signaling pathways remain vaguely defined. Here, we show that mammalian target of rapamycin (mTOR) signaling is pivotal i...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Paliouras, Grigorios N., Hamilton, Laura K., Aumont, Anne, Joppé, Sandra E., Barnabé-Heider, Fanie, Fernandes, Karl J. L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2012
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704835/
https://ncbi.nlm.nih.gov/pubmed/23100423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2248-12.2012
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