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Mammalian Target of Rapamycin Signaling Is a Key Regulator of the Transit-Amplifying Progenitor Pool in the Adult and Aging Forebrain

Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles of key intracellular signaling pathways remain vaguely defined. Here, we show that mammalian target of rapamycin (mTOR) signaling is pivotal i...

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書誌詳細
出版年:J Neurosci
主要な著者: Paliouras, Grigorios N., Hamilton, Laura K., Aumont, Anne, Joppé, Sandra E., Barnabé-Heider, Fanie, Fernandes, Karl J. L.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704835/
https://ncbi.nlm.nih.gov/pubmed/23100423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2248-12.2012
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