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B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

B-1a cells play an important role in mediating tissue homeostasis and protecting against infections. They are the main producers of ‘natural’ IgM, spontaneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylcholine (PtC), or antigens expressed by the intestinal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Kreuk, Lieselotte SM, Koch, Meghan A, Slayden, Leianna C, Lind, Nicholas A, Chu, Sophia, Savage, Hannah P, Kantor, Aaron B, Baumgarth, Nicole, Barton, Gregory M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703855/
https://ncbi.nlm.nih.gov/pubmed/31433298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47015
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