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B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota
B-1a cells play an important role in mediating tissue homeostasis and protecting against infections. They are the main producers of ‘natural’ IgM, spontaneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylcholine (PtC), or antigens expressed by the intestinal...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6703855/ https://ncbi.nlm.nih.gov/pubmed/31433298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47015 |
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