B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

B-1a cells play an important role in mediating tissue homeostasis and protecting against infections. They are the main producers of ‘natural’ IgM, spontaneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylcholine (PtC), or antigens expressed by the intestinal...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Kreuk, Lieselotte SM, Koch, Meghan A, Slayden, Leianna C, Lind, Nicholas A, Chu, Sophia, Savage, Hannah P, Kantor, Aaron B, Baumgarth, Nicole, Barton, Gregory M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Immunology and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703855/
https://ncbi.nlm.nih.gov/pubmed/31433298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47015
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi