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Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)
BACKGROUND: Large clonal populations of cells bearing PIG-A mutations are the sine qua non of PNH, but the PIG-A mutation itself is insufficient for clonal expansion. The association between PNH and aplastic anemia supports the immune escape model, but not all PNH patients demonstrate a history of a...
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| 發表在: | Exp Hematol Oncol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702710/ https://ncbi.nlm.nih.gov/pubmed/31453016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0142-0 |
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