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The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH)

Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by the presence in the patient's hematopoietic system of a large cell population with a mutation in the X-linked PIG-A gene. Although this abnormal cell population is often found to be monoclonal, it is not unusual that 2 or even severa...

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Autors principals: Araten, David J., Luzzatto, Lucio
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895494/
https://ncbi.nlm.nih.gov/pubmed/16543465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-01-0256
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