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Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)
BACKGROUND: Large clonal populations of cells bearing PIG-A mutations are the sine qua non of PNH, but the PIG-A mutation itself is insufficient for clonal expansion. The association between PNH and aplastic anemia supports the immune escape model, but not all PNH patients demonstrate a history of a...
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| Udgivet i: | Exp Hematol Oncol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702710/ https://ncbi.nlm.nih.gov/pubmed/31453016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0142-0 |
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