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Leukemic Blasts with the Paroxysmal Nocturnal Hemoglobinuria Phenotype in Children with Acute Lymphoblastic Leukemia
It has been proposed that genomic instability is essential to account for the multiplicity of mutations often seen in malignancies. Using the X-linked PIG-A gene as a sentinel gene for spontaneous inactivating somatic mutations, we previously showed that healthy individuals harbor granulocytes with...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483812/ https://ncbi.nlm.nih.gov/pubmed/22940070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.07.025 |
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