Leukemic Blasts with the Paroxysmal Nocturnal Hemoglobinuria Phenotype in Children with Acute Lymphoblastic Leukemia

It has been proposed that genomic instability is essential to account for the multiplicity of mutations often seen in malignancies. Using the X-linked PIG-A gene as a sentinel gene for spontaneous inactivating somatic mutations, we previously showed that healthy individuals harbor granulocytes with...

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Autores principales: Araten, David J., Sanders, Katie J., Anscher, Dan, Zamechek, Leah, Hunger, Stephen P., Ibrahim, Sherif
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2012
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483812/
https://ncbi.nlm.nih.gov/pubmed/22940070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.07.025
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