USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

The antiviral activity of host factor apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G (APOBEC3G, A3G) and its degradation mediated by human immunodeficiency virus type 1 (HIV-1) Vif protein are important topics. Although accumulating evidence indicates the importance of deubiquiti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pan, Ting, Song, Zheng, Wu, Liyang, Liu, Guangyan, Ma, Xiancai, Peng, Zhilin, Zhou, Mo, Liang, Liting, Liu, Bingfeng, Liu, Jun, Zhang, Junsong, Zhang, Xuanhong, Huang, Ryan, Zhao, Jiacong, Li, Yonghong, Ling, Xuemei, Luo, Yuewen, Tang, Xiaoping, Cai, Weiping, Deng, Kai, Li, Linghua, Zhang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701944/
https://ncbi.nlm.nih.gov/pubmed/31397674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48318
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