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TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb
Comprehensively elucidating the molecular mechanisms of human immunodeficiency virus type 1 (HIV-1) latency is a priority to achieve a functional cure. As current 'shock' agents failed to efficiently reactivate the latent reservoir, it is important to discover new targets for developing mo...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6361614/ https://ncbi.nlm.nih.gov/pubmed/30652970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42426 |
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