Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation

Long noncoding RNAs (lncRNAs) play multiple key regulatory roles in various cellular pathways. However, their functions in HIV-1 latent infection remain largely unknown. Here we show that a lncRNA named NRON, which is highly expressed in resting CD4(+) T lymphocytes, could be involved in HIV-1 laten...

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Udgivet i:Nat Commun
Main Authors: Li, Jun, Chen, Cancan, Ma, Xiancai, Geng, Guannan, Liu, Bingfeng, Zhang, Yijun, Zhang, Shaoyang, Zhong, Fudi, Liu, Chao, Yin, Yue, Cai, Weiping, Zhang, Hui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909936/
https://ncbi.nlm.nih.gov/pubmed/27291871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11730
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