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Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
BACKGROUND: Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. METHODS: Here we employed biochemical approaches and cellular analyses to evaluat...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Commun Signal |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6700787/ https://ncbi.nlm.nih.gov/pubmed/31429758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0407-6 |
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