Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

Integrin activation, the rapid conversion of integrin adhesion receptors from low to high affinity, occurs in response to intracellular signals that act on the short cytoplasmic tails of integrin β subunits. Talin binding to integrin β tails provides one key activation signal, but additional factors...

Full description

Saved in:
Bibliographic Details
Main Authors: Harburger, David S., Bouaouina, Mohamed, Calderwood, David A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670154/
https://ncbi.nlm.nih.gov/pubmed/19240021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809233200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items