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Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

Integrin activation, the rapid conversion of integrin adhesion receptors from low to high affinity, occurs in response to intracellular signals that act on the short cytoplasmic tails of integrin β subunits. Talin binding to integrin β tails provides one key activation signal, but additional factors...

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Detalhes bibliográficos
Main Authors: Harburger, David S., Bouaouina, Mohamed, Calderwood, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670154/
https://ncbi.nlm.nih.gov/pubmed/19240021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809233200
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