Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase

Integrins are heterodimeric α/β extracellular matrix adhesion receptors that couple physically to the actin cytoskeleton and regulate kinase signaling pathways to control cytoskeletal remodeling and adhesion complex formation and disassembly. β1 integrins signal through the Abl2/Arg (Abl-related gen...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Simpson, Mark A., Bradley, William D., Harburger, David, Parsons, Maddy, Calderwood, David A., Koleske, Anthony J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375489/
https://ncbi.nlm.nih.gov/pubmed/25694433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638874
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