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Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase

Integrins are heterodimeric α/β extracellular matrix adhesion receptors that couple physically to the actin cytoskeleton and regulate kinase signaling pathways to control cytoskeletal remodeling and adhesion complex formation and disassembly. β1 integrins signal through the Abl2/Arg (Abl-related gen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Simpson, Mark A., Bradley, William D., Harburger, David, Parsons, Maddy, Calderwood, David A., Koleske, Anthony J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375489/
https://ncbi.nlm.nih.gov/pubmed/25694433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638874
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