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Structure of the ABL2/ARG kinase in complex with dasatinib

ABL2/ARG (ABL-related gene) belongs to the ABL (Abelson tyrosine-protein kinase) family of tyrosine kinases. ARG plays important roles in cell morphogenesis, motility, growth and survival, and many of these biological roles overlap with the cellular functions of the ABL kinase. Chronic myeloid leuke...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Ha, Byung Hak, Simpson, Mark Adam, Koleske, Anthony J., Boggon, Titus J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388181/
https://ncbi.nlm.nih.gov/pubmed/25849507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004793
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