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Structure of the ABL2/ARG kinase in complex with dasatinib

ABL2/ARG (ABL-related gene) belongs to the ABL (Abelson tyrosine-protein kinase) family of tyrosine kinases. ARG plays important roles in cell morphogenesis, motility, growth and survival, and many of these biological roles overlap with the cellular functions of the ABL kinase. Chronic myeloid leuke...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Crystallogr F Struct Biol Commun
Egile Nagusiak: Ha, Byung Hak, Simpson, Mark Adam, Koleske, Anthony J., Boggon, Titus J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388181/
https://ncbi.nlm.nih.gov/pubmed/25849507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004793
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