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Structure of the ABL2/ARG kinase in complex with dasatinib

ABL2/ARG (ABL-related gene) belongs to the ABL (Abelson tyrosine-protein kinase) family of tyrosine kinases. ARG plays important roles in cell morphogenesis, motility, growth and survival, and many of these biological roles overlap with the cellular functions of the ABL kinase. Chronic myeloid leuke...

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Bibliografiska uppgifter
I publikationen:Acta Crystallogr F Struct Biol Commun
Huvudupphovsmän: Ha, Byung Hak, Simpson, Mark Adam, Koleske, Anthony J., Boggon, Titus J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388181/
https://ncbi.nlm.nih.gov/pubmed/25849507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004793
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