p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

Recent studies show p85α up-regulates epidermal growth factor (EGF) receptor, thereby promoting malignant cell transformation and migration in normal mouse embryonic fibroblasts (MEFs). However, the potential role of p85α in human bladder cancer (BC) remains unknown. Here, we show that p85α is down-...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neoplasia
Autori principali: Wang, Jingjing, Zhang, Ning, Peng, Minggang, Hua, Xiaohui, Huang, Chao, Tian, Zhongxian, Xie, Qipeng, Zhu, Junlan, Li, Jingxia, Huang, Haishan, Huang, Chuanshu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2019
Soggetti:
Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700442/
https://ncbi.nlm.nih.gov/pubmed/31401412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.07.007
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi