p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

Recent studies show p85α up-regulates epidermal growth factor (EGF) receptor, thereby promoting malignant cell transformation and migration in normal mouse embryonic fibroblasts (MEFs). However, the potential role of p85α in human bladder cancer (BC) remains unknown. Here, we show that p85α is down-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neoplasia
Prif Awduron: Wang, Jingjing, Zhang, Ning, Peng, Minggang, Hua, Xiaohui, Huang, Chao, Tian, Zhongxian, Xie, Qipeng, Zhu, Junlan, Li, Jingxia, Huang, Haishan, Huang, Chuanshu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2019
Pynciau:
Original article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700442/
https://ncbi.nlm.nih.gov/pubmed/31401412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.07.007
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