p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

Recent studies show p85α up-regulates epidermal growth factor (EGF) receptor, thereby promoting malignant cell transformation and migration in normal mouse embryonic fibroblasts (MEFs). However, the potential role of p85α in human bladder cancer (BC) remains unknown. Here, we show that p85α is down-...

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Publicado en:Neoplasia
Main Authors: Wang, Jingjing, Zhang, Ning, Peng, Minggang, Hua, Xiaohui, Huang, Chao, Tian, Zhongxian, Xie, Qipeng, Zhu, Junlan, Li, Jingxia, Huang, Haishan, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2019
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700442/
https://ncbi.nlm.nih.gov/pubmed/31401412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.07.007
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