XIAP Interaction with E2F1 and Sp1 via its BIR2 and BIR3 domains specific activated MMP2 to promote bladder cancer invasion

XIAP has generally been thought to function in bladder cancer. However, the potential function of structure-based function of XIAP in human BC invasion has not been well explored before. We show here that ectopic expression of the BIR domains of XIAP specifically resulted in MMP2 activation and cell...

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Publicado no:Oncogenesis
Main Authors: Xu, Jiheng, Hua, Xiaohui, Yang, Rui, Jin, Honglei, Li, Jingxia, Zhu, Junlan, Tian, Zhongxian, Huang, Maowen, Jiang, Guosong, Huang, Haishan, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898186/
https://ncbi.nlm.nih.gov/pubmed/31811115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0181-8
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