Expression and Role of Methylenetetrahydrofolate Dehydrogenase 1 Like (MTHFD1L) in Bladder Cancer

Cancer cells utilize vitamin folate to fulfill their excessive demand for nucleotides and amino acids. Dihydrofolate reductase (DHFR), an enzyme involved in folate metabolism converts dihydrofolate into tetrahydrofolate, which is required for the de novo synthesis of purines, and certain amino acids...

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Bibliografiska uppgifter
I publikationen:Transl Oncol
Huvudupphovsmän: Eich, Marie-Lisa, Rodriguez Pena, Maria Del Carmen, Chandrashekar, Darshan Shimoga, Chaux, Alcides, Agarwal, Sumit, Gordetsky, Jennifer B., Ferguson, James E., Sonpavde, Guru P., Netto, George J., Varambally, Sooryanarayana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2019
Ämnen:
Original article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700437/
https://ncbi.nlm.nih.gov/pubmed/31401334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.07.012
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