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Expression and Role of Methylenetetrahydrofolate Dehydrogenase 1 Like (MTHFD1L) in Bladder Cancer

Cancer cells utilize vitamin folate to fulfill their excessive demand for nucleotides and amino acids. Dihydrofolate reductase (DHFR), an enzyme involved in folate metabolism converts dihydrofolate into tetrahydrofolate, which is required for the de novo synthesis of purines, and certain amino acids...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Transl Oncol
Päätekijät: Eich, Marie-Lisa, Rodriguez Pena, Maria Del Carmen, Chandrashekar, Darshan Shimoga, Chaux, Alcides, Agarwal, Sumit, Gordetsky, Jennifer B., Ferguson, James E., Sonpavde, Guru P., Netto, George J., Varambally, Sooryanarayana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Neoplasia Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700437/
https://ncbi.nlm.nih.gov/pubmed/31401334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.07.012
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