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Defective Circadian Control in Mesenchymal Cells Reduces Adult Bone Mass in Mice by Promoting Osteoclast Function

Serum bone turnover markers show diurnal variation in humans, suggesting that circadian rhythms contribute to normal bone physiology. This conclusion is corroborated by bone phenotypes in mice with genetic disruption of the circadian molecular clock mechanism, for instance via deletion of the transc...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Tsang, Kelly, Liu, Haoming, Yang, Yen, Charles, Julia F., Ermann, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699618/
https://ncbi.nlm.nih.gov/pubmed/30659979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.01.016
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