Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass

Ataxia-telangiectasia mutated (ATM) kinase is a central component involved in the signal transduction of the DNA damage response (DDR) and thus plays a critical role in the maintenance of genomic integrity. Although the primary functions of ATM are associated with the DDR, emerging data suggest that...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Hirozane, Toru, Tohmonda, Takahide, Yoda, Masaki, Shimoda, Masayuki, Kanai, Yae, Matsumoto, Morio, Morioka, Hideo, Nakamura, Masaya, Horiuchi, Keisuke
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039636/
https://ncbi.nlm.nih.gov/pubmed/27677594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34426
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky