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Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass
Ataxia-telangiectasia mutated (ATM) kinase is a central component involved in the signal transduction of the DNA damage response (DDR) and thus plays a critical role in the maintenance of genomic integrity. Although the primary functions of ATM are associated with the DDR, emerging data suggest that...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039636/ https://ncbi.nlm.nih.gov/pubmed/27677594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34426 |
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