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Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis
Bone surfaces attract hematopoietic and nonhematopoietic cells, such as osteoclasts (OCs) and osteoblasts (OBs), and are targeted by bone metastatic cancers. However, the mechanisms guiding cells toward bone surfaces are essentially unknown. Here, we show that the Gαi protein–coupled receptor (GPCR)...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612084/ https://ncbi.nlm.nih.gov/pubmed/26438360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150088 |
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