Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

Osteoclasts (OCs) are bone-resorbing multinuclear giant cells that differentiate from mononuclear macrophage/monocyte-lineage hematopoietic precursors. Although many molecules are known to contribute to OC differentiation, RANKL chief among them, the mechanisms controlling the recruitment and homing...

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Библиографические подробности
Главные авторы: Ishii, Masaru, Egen, Jackson G., Klauschen, Frederick, Meier-Schellersheim, Martin, Saeki, Yukihiko, Vacher, Jean, Proia, Richard L., Germain., Ronald N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785034/
https://ncbi.nlm.nih.gov/pubmed/19204730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07713
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