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Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis
Osteoclasts (OCs) are bone-resorbing multinuclear giant cells that differentiate from mononuclear macrophage/monocyte-lineage hematopoietic precursors. Although many molecules are known to contribute to OC differentiation, RANKL chief among them, the mechanisms controlling the recruitment and homing...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785034/ https://ncbi.nlm.nih.gov/pubmed/19204730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07713 |
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