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Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo
Sphingosine-1-phosphate (S1P), a lipid mediator enriched in blood, controls the dynamic migration of osteoclast (OC) precursors (OPs) between the blood and bone, in part via the S1P receptor 1 (S1PR1) which directs positive chemotaxis toward S1P. We show that OPs also express S1PR2, an S1P receptor...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3005230/ https://ncbi.nlm.nih.gov/pubmed/21135136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101474 |
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