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Defective Circadian Control in Mesenchymal Cells Reduces Adult Bone Mass in Mice by Promoting Osteoclast Function

Serum bone turnover markers show diurnal variation in humans, suggesting that circadian rhythms contribute to normal bone physiology. This conclusion is corroborated by bone phenotypes in mice with genetic disruption of the circadian molecular clock mechanism, for instance via deletion of the transc...

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Dettagli Bibliografici
Pubblicato in:Bone
Autori principali: Tsang, Kelly, Liu, Haoming, Yang, Yen, Charles, Julia F., Ermann, Joerg
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699618/
https://ncbi.nlm.nih.gov/pubmed/30659979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.01.016
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