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Fluid Shear Stress Increases Osteocyte and Inhibits Osteoclasts via Downregulating Receptor-Activator of Nuclear Factor κB (RANK)/Osteoprotegerin Expression in Myeloma Microenvironment
BACKGROUND: The aim of this study was to determine the effects of myeloma cells exposed to fluid shear stress on osteocytes and osteoclasts, and clarify the potential underlying mechanisms. MATERIAL/METHODS: A flow and a non-flow model were established using a flow fluid chamber. The myeloma cell li...
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| Publicado en: | Med Sci Monit |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Scientific Literature, Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6699202/ https://ncbi.nlm.nih.gov/pubmed/31400110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915986 |
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