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miR-145-5p Increases Osteoclast Numbers In Vitro and Aggravates Bone Erosion in Collagen-Induced Arthritis by Targeting Osteoprotegerin

BACKGROUND: Osteoprotegerin (OPG) inhibits bone resorption and binds with strong affinity to receptor activator of NF κB ligand (RANKL), thereby preventing RANKL from binding to its receptor RANK. Osteoclasts have documented effects on bone erosion of rheumatoid arthritis (RA). The aim of this study...

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書目詳細資料
發表在:Med Sci Monit
Main Authors: Chen, Yaqing, Wang, Xiaoxue, Yang, Mengchen, Ruan, Wendong, Wei, Wei, Gu, Dongmei, Wang, Jing, Guo, Xinling, Guo, Lingxia, Yuan, Yuhua
格式: Artigo
語言:Inglês
出版: International Scientific Literature, Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080580/
https://ncbi.nlm.nih.gov/pubmed/30059491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908219
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