Osteoprotegerin Reduces Osteoclast Numbers and Prevents Bone Erosion in Collagen-Induced Arthritis

Rheumatoid arthritis is characterized by progressive synovial inflammation and joint destruction. While matrix metalloproteinases (MMPs) are implicated in the erosion of unmineralized cartilage, bone destruction involves osteoclasts, the specialized cells that resorb calcified bone matrix. RANK liga...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Romas, Evan, Sims, Natalie A., Hards, Daphne K., Lindsay, Mandy, Quinn, Julian W.M., Ryan, Peter F.J., Dunstan, Colin R., Martin, T. John, Gillespie, Matthew T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867274/
https://ncbi.nlm.nih.gov/pubmed/12368214
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky