Osteoprotegerin Reduces Osteoclast Numbers and Prevents Bone Erosion in Collagen-Induced Arthritis

Rheumatoid arthritis is characterized by progressive synovial inflammation and joint destruction. While matrix metalloproteinases (MMPs) are implicated in the erosion of unmineralized cartilage, bone destruction involves osteoclasts, the specialized cells that resorb calcified bone matrix. RANK liga...

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Detaylı Bibliyografya
Asıl Yazarlar: Romas, Evan, Sims, Natalie A., Hards, Daphne K., Lindsay, Mandy, Quinn, Julian W.M., Ryan, Peter F.J., Dunstan, Colin R., Martin, T. John, Gillespie, Matthew T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2002
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867274/
https://ncbi.nlm.nih.gov/pubmed/12368214
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