Osteoprotegerin Reduces Osteoclast Numbers and Prevents Bone Erosion in Collagen-Induced Arthritis

Rheumatoid arthritis is characterized by progressive synovial inflammation and joint destruction. While matrix metalloproteinases (MMPs) are implicated in the erosion of unmineralized cartilage, bone destruction involves osteoclasts, the specialized cells that resorb calcified bone matrix. RANK liga...

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Xehetasun bibliografikoak
Egile Nagusiak: Romas, Evan, Sims, Natalie A., Hards, Daphne K., Lindsay, Mandy, Quinn, Julian W.M., Ryan, Peter F.J., Dunstan, Colin R., Martin, T. John, Gillespie, Matthew T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2002
Gaiak:
Regular Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867274/
https://ncbi.nlm.nih.gov/pubmed/12368214
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