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Genome editing via delivery of Cas9 ribonucleoprotein

The CRISPR-Cas genome editing system is very powerful. The format of the CRISPR reagents and the means of delivery are often important factors in targeting efficiency. Delivery of recombinant Cas9 protein and guide RNA (gRNA) as a preformed ribonucleoprotein (RNP) complex has recently emerged as a p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods
Main Authors: DeWitt, Mark A., Corn, Jacob E., Carroll, Dana
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698184/
https://ncbi.nlm.nih.gov/pubmed/28410976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2017.04.003
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