Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription

Adeno-associated viruses (AAV) are Dependoparvoviruses that have shown promise as recombinant vectors for gene therapy. While infectious pathways of AAV are well studied, gaps remain in our understanding of host factors affecting vector genome expression. Here, we map the role of ring finger protein...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Madigan, Victoria J., Yuziuk, Julianne A., Chiarella, Anna M., Tyson, Tyne O., Meganck, Rita M., Elmore, Zachary C., Tse, Longping V., Hathaway, Nathaniel A., Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697353/
https://ncbi.nlm.nih.gov/pubmed/31386698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007988
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