Combined Antitumor Effects of Sorafenib and GPC3-CAR T Cells in Mouse Models of Hepatocellular Carcinoma

Our previous study indicated that GPC3-targeted chimeric antigen receptor (CAR) T cell therapy has a high safety profile in patients with hepatocellular carcinoma (HCC). However, the response rate requires further improvement. Here, we analyzed the combined effect of GPC3-CAR T cells and sorafenib i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther
Egile Nagusiak: Wu, Xiuqi, Luo, Hong, Shi, Bizhi, Di, Shengmeng, Sun, Ruixin, Su, Jingwen, Liu, Ying, Li, Hua, Jiang, Hua, Li, Zonghai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697347/
https://ncbi.nlm.nih.gov/pubmed/31078430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.04.020
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