Development of GPC3-Specific Chimeric Antigen Receptor-Engineered Natural Killer Cells for the Treatment of Hepatocellular Carcinoma

Chimeric antigen receptor (CAR)-modified natural killer (NK) cells represent a promising immunotherapeutic modality for cancer treatment. However, their potential utilities have not been explored in hepatocellular carcinoma (HCC). Glypian-3 (GPC3) is a rational immunotherapeutic target for HCC. In t...

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Pubblicato in:Mol Ther
Autori principali: Yu, Min, Luo, Hong, Fan, Mingliang, Wu, Xiuqi, Shi, Bizhi, Di, Shengmeng, Liu, Ying, Pan, Zeyan, Jiang, Hua, Li, Zonghai
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835122/
https://ncbi.nlm.nih.gov/pubmed/29339014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.12.012
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