GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer

GRP78 conducts protein folding and quality control in the ER and shows elevated expression and cell surface translocation in advanced tumors. However, the underlying mechanisms enabling GRP78 to exert novel signaling functions at cell surface are just emerging. CD44 is a transmembrane protein and an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Life Sci Alliance
Main Authors: Tseng, Chun-Chih, Stanciauskas, Ramunas, Zhang, Pu, Woo, Dennis, Wu, Kaijin, Kelly, Kevin, Gill, Parkash S, Yu, Min, Pinaud, Fabien, Lee, Amy S
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696983/
https://ncbi.nlm.nih.gov/pubmed/31416894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900377
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