The COOH-Terminal Proline-Rich Region of GRP78 Is a Key Regulator of Its Cell Surface Expression and Viability of Tamoxifen-Resistant Breast Cancer Cells()

Translocation of 78-kDa glucose-regulated protein (GRP78) from endoplasmic reticulum (ER) to plasma membrane represents a paradigm shift beyond its traditional function as an ER chaperone protein. Cell surface GRP78 (csGRP78) exerts novel signaling functions, and mechanisms underlying its cell surfa...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Tseng, Chun-Chih, Zhang, Pu, Lee, Amy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2019
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629921/
https://ncbi.nlm.nih.gov/pubmed/31306849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.05.008
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