Loading...

Reduced model to predict thrombin and fibrin during thrombosis on collagen/tissue factor under venous flow: Roles of γ’-fibrin and factor XIa

During thrombosis, thrombin generates fibrin, however fibrin reversibly binds thrombin with low affinity E-domain sites (K(D) = 2.8 μM) and high affinity γ’-fibrin sites (K(D) = 0.1 μM). For blood clotting on collagen/tissue factor (1 TF-molecule/μm(2)) at 200 s(-1) wall shear rate, high μM-levels o...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Chen, Jason, Diamond, Scott L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695209/
https://ncbi.nlm.nih.gov/pubmed/31381558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007266
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!