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Thrombus growth and embolism on tissue factor-bearing collagen surfaces under flow: Role of thrombin with and without fibrin

OBJECTIVES: At sites of vascular injury thrombin is an important mediator in thrombus growth and stability. Using microfluidic flow devices as well as patterned surfaces of collagen and tissue factor we sought to determine the role that fibrin plays in clot stability without interfering with the pro...

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Detalhes bibliográficos
Main Authors: Colace, T., Muthard, R., Diamond, S.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418805/
https://ncbi.nlm.nih.gov/pubmed/22516070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.249789
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