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Establishing the Transient Mass Balance of Thrombosis: From Tissue Factor to Thrombin to Fibrin Under Venous Flow

OBJECTIVE—: We investigated the coregulation of thrombin and fibrin as blood flows over a procoagulant surface. APPROACH AND RESULTS—: Using microfluidic perfusion of factor XIIa-inhibited human whole blood (200 s(−1) wall shear rate) over a 250-μm long patch of collagen/TF (tissue factor; ≈1 molecu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Zhu, Shu, Chen, Jason, Diamond, Scott L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023760/
https://ncbi.nlm.nih.gov/pubmed/29724819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310906
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