PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

One of the most frequently mutated proteins in human B-lineage leukemia is the transcription factor PAX5. These mutations often result in partial rather than complete loss of function of the transcription factor. While the functional dose of PAX5 has a clear connection to human malignancy, there is...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Okuyama, Kazuki, Strid, Tobias, Kuruvilla, Jacob, Somasundaram, Rajesh, Cristobal, Susana, Smith, Emma, Prasad, Mahadesh, Fioretos, Thoas, Lilljebjörn, Henrik, Soneji, Shamit, Lang, Stefan, Ungerbäck, Jonas, Sigvardsson, Mikael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695195/
https://ncbi.nlm.nih.gov/pubmed/31381561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008280
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