EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a protein of critical importance for lineage specific...

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Gardado en:
Detalles Bibliográficos
Publicado en:Blood
Main Authors: Somasundaram, Rajesh, Jensen, Christina T., Tingvall-Gustafsson, Johanna, Åhsberg, Josefine, Okuyama, Kazuki, Prasad, Mahadesh, Hagman, James R., Wang, Xun, Soneji, Shamit, Strid, Tobias, Ungerbäck, Jonas, Sigvardsson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2021
Assuntos:
Hematopoiesis and Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176764/
https://ncbi.nlm.nih.gov/pubmed/33619557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009564
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