Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency

Early B-cell factor 1 (Ebf1) is a transcription factor with documented dose-dependent functions in normal and malignant B-lymphocyte development. To understand more about the roles of Ebf1 in malignant transformation, we investigated the impact of reduced functional Ebf1 dosage on mouse B-cell proge...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood
Autors principals: Prasad, Mahadesh A. J., Ungerbäck, Jonas, Åhsberg, Josefine, Somasundaram, Rajesh, Strid, Tobias, Larsson, Malin, Månsson, Robert, De Paepe, Ayla, Lilljebjörn, Henrik, Fioretos, Thoas, Hagman, James, Sigvardsson, Mikael
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481594/
https://ncbi.nlm.nih.gov/pubmed/25838350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-617282
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars